Clinical Trial Enrollment Intelligence

Enrollment Delays Kill Phase III Timelines. EHR Phenotyping Fixes That.

TrialVyx matches eligible patients to open trial slots using de-identified EHR phenotype signals — reducing the 18-month enrollment window to under 9 months without adding sites.

80%
of Phase III trials miss enrollment deadlines
18 mo
average enrollment window industry-wide
~30%
of total trial cost is patient recruitment
EHR Phenotype Matching

From Patient Records to Trial-Ready Referrals

TrialVyx ingests de-identified EHR phenotype signals from partner sites and uses protocol-aware AI to match patients against open trial inclusion/exclusion criteria — in real time. No PHI transmitted. No manual chart review.

  • FHIR R4 compatible EHR data ingestion
  • De-identified phenotype extraction — no PHI leaves the site
  • Real-time match scoring against open trial protocols
  • Pre-screened referral delivery to sites — 47% lower screen failure
EHR Data FHIR R4 Phenotype Engine Trial Criteria Match Score Site Assignment Pre-Screened Referral Step 1 Step 2 Step 3 Step 4 Step 5: Enrolled Faster
Who We Serve

Built for Both Sides of the Trial

For Sponsors

Cut Enrollment Timelines

Phase II/III sponsors using TrialVyx get AI-matched, pre-screened referrals across their site network — accelerating enrollment and reducing per-patient recruitment cost.

  • Reduce enrollment window from months to weeks
  • AI site selection based on real patient population signals
  • Real-time enrollment dashboard across all sites
  • Lower cost per enrolled patient
Sponsor Solutions
For Sites

Receive Pre-Screened Patients

Clinical research sites partnering with TrialVyx receive high-quality patient referrals matched to active trial criteria — reducing screen failure waste and coordinator burden.

  • Pre-screened referrals — fewer wasted screen visits
  • Reduced coordinator workload on eligibility review
  • Visibility into your site's enrollment performance
  • Access to more sponsored trial opportunities
Site Solutions
Enrollment Intelligence Platform

Real-Time Enrollment Intelligence

Track site performance, monitor patient match scores, and act on enrollment signals — all from a single dashboard built for clinical operations teams.

Abstract clinical enrollment dashboard visualization
The Process

Three Steps to Faster Enrollment

01

Connect EHR

FHIR-compatible data ingestion. De-identified phenotype extraction from partner EHR systems. No PHI transmitted.

02

AI Matching

Criteria mapping against open trial protocols. Real-time scoring of patient eligibility. Continuous protocol updates.

03

Enroll Faster

Sites receive pre-screened referrals. Sponsors see enrollment acceleration. Dashboard tracks progress in real time.

See the Full Process
Oncology · Phase III

Enrollment Window Cut from 22 Months to 11 Months

A Phase III oncology sponsor deployed TrialVyx across 14 sites. AI phenotype matching reduced screen failure rate by 52% and hit enrollment targets in half the projected time.

Read Case Study
Time to Enrollment Target
11 mo
vs. 22-month projection
View Full Case Study
What Clinical Leaders Say
"The EHR phenotyping approach caught eligible patients our traditional site activation process was completely missing. We enrolled 40% faster than our last comparable trial — and the site coordinators told us the referral quality was the highest they'd seen."
Portrait of VP Clinical Operations
VP Clinical Operations
Mid-size oncology-focused biopharma sponsor